Does a man’s age affect the quality of his sperm?

Advanced paternal age is generally defined as above 35-40 years and is associated with a decrease in the quality of sperm analysis parameters. Men over 45 years of age take about 5 times longer to achieve pregnancy compared to men under 25 years of age. Additionally, there is evidence that advanced paternal age increases the risk of miscarriage, birth defects, and autism. Men over 40-45 years of age are twice as likely to have an autistic child and a five times greater risk of having a child with schizophrenia.

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