What is Antiphospholipid Syndrome?

The antiphospholipid syndrome (SAP) is an entity with definite clinical and analytical features independent of other autoimmune entities. The etiopathogenesis of the condition is unknown. This means that the mechanism by which antiphospholipid antibodies cause fetal losses is not known. However, it seems that a clotting phenomenon (thrombosis) may be at the root of the problem.

Ultimately, pregnant patients affected by SAP are at risk for recurrent miscarriages and late recurrent fetal losses. Therefore, it is mandatory that this syndrome be ruled out in these patients, determining the possible presence of APL or ACA.

After ruling out other causes of abortion, and once a picture of SAP has been diagnosed, the treatment will be based, fundamentally, on drugs with antiaggregant effect (acetylsalicylic acid) and/or anticoagulant (Heparin).

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