What is Globozoospermia?

Globozoospermic sperm are shaped like a balloon, hence the name. These sperm do not have an acrosome, a small deposit at the end of the head that contains a substance capable of degrading the egg’s covering and that allows the sperm to penetrate inside.

For this reason, the balloon-shaped sperm will not be able to fertilize the egg naturally, or with techniques such as artificial insemination or conventional IVF. Only with IVF-ICSI, in which the embryologist introduces the sperm directly into the egg with microinjection, will fertilization be possible.

Even so, it is unlikely to achieve a viable pregnancy with Globozoospermia, since these sperm, in addition to not having an acrosome, can have their genetic load altered.

Leave a Comment